Some Australian researchers have developed a revolutionary drug that has the hope of treating the debilitating and fatal disease of motor neurons.
The result of 15 years of work has been tested on 32 patients in Melbourne and Sydney and has shown that it could slow down the progression of the disease, rather than treat the symptoms.
"It's a huge breakthrough," said Professor Ashley Bush, chief scientific officer of collaborative medical development and director of the Melbourne Research Center,
"This is the first human trial for a drug that modifies the disease for motoneuron disease "
" We can not wait to confirm the positive results in a larger study soon. "
After six months, copper- The administration drug CuATSM showed the progression of the disease in patients slowed by about 70%.
Participants have improved lung function and cognition and a reduction in the decline of their motor disability.
Neurons disease is a progressive and fatal neurodegenerative disease with the death of brain cells that control muscle movements, eventually causing paralysis.
Patients usually die of respiratory failure within three years of diagnosis and there are no treatments or therapies available. [1
"It is gratifying to see such promising results made possible by the collaborative fundamental research at the interface between chemistry and biology ", University of Melbourne Professor Paul Donnelly said.
The drug is also tested on patients with Parkinson's disease.
The research came after the establishment of the Fight MND organization in 2014 by the co-founder and former head coach of the Melbourne football club, Neale Daniher.  Mr. Daniher became public with his diagnosis and fights the disease to raise money and awareness to help find a cure.
The discoveries, by researchers from the Florey Institute and the University of Melbourne, were presented at the International Symposium on ALS / MND in Glasgow, Scotland.